标题:CRL4B interacts and coordinates with SIN3A/HDAC complex to repress CDKN1A in driving cell cycle progression
作者:Qinghong Ji;Huili Hu;Fan Yang;Jupeng Yuan;Yang Yang;Liangqian Jiang;Yanyan Qian;Baichun Jiang;Yongxin Zou;Yan Wang;Changshun Shao;Yaoqin Gong;
作者机构:[Qinghong Ji;Huili Hu;Fan Yang;Jupeng Yuan;Yang Yang;Liangqian Jiang;Yanyan Qian;Baichun Jiang;Yongxin Zou;Yan Wang;Changshun Shao;Yaoqin Gong]Key Lab 更多
会议名称:2014全球华人遗传学大会全国第十三次医学遗传学学术会议
来源:2014全球华人遗传学大会全国第十三次医学遗传学学术会议论文汇编
出版年:2014
关键词:HDAC;cell;CRL4B interacts and coordinates with SIN3A/HDAC complex to repress CDKN1A in driving cell cycle progression;cycle;
摘要:CUL4B,a scaffold protein that assembles CRIAB ubiquitin ligase complex,participates in the regulation of a broad spectrum of biological processes.We here demonstrated a critical role of CUIAB in driving cell cycle progression.We showed that loss of CUL4B resulted in a significantly reduced cell p...
资源类型:会议论文
原文链接:http://kns.cnki.net/kns/detail/detail.aspx?FileName=ZGYL201410002284&DbName=IPFD2014
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