标题:Cobalt-catalyzed radical cyclization of isocyanides forming phenanthridine derivatives
作者:Liu, Xiangyu; Wu, Chengjuan; Zhang, Jing; Shi, Yihan; Zhang, Shengnan; Geng, Yan; Tung, Chen-Ho; Wang, Wenguang
作者机构:[Liu, Xiangyu; Wu, Chengjuan; Zhang, Jing; Shi, Yihan; Zhang, Shengnan; Tung, Chen-Ho; Wang, Wenguang] Shandong Univ, Sch Chem & Chem Engn, Minist Edu 更多
通讯作者:Wu, CJ;Wang, WG;Wu, Chengjuan
通讯作者地址:[Wu, CJ; Wang, WG]Shandong Univ, Sch Chem & Chem Engn, Minist Educ, Key Lab Colloid & Interface Chem, 27 South Shanda Rd, Jinan 250100, Shandong, Peop 更多
来源:ORGANIC CHEMISTRY FRONTIERS
出版年:2018
卷:5
期:20
页码:2997-3002
DOI:10.1039/c8qo00887f
摘要:A neutral cobalt(ii) compound Cp*Co(1,2-Ph2PC6H4S) (1, Cp* = Me5C5-) catalyzes the radical cyclization of 2-isocyano-biphenyls with alkyl halides, providing a variety of 6-substituted phenanthridines and phenanthridine-fused polycyclic compounds in good to excellent yields. The mild reaction conditions allow the catalysis to tolerate various alkyl halides for scaled-up syntheses. Polycyclic compounds with a 6-ethylpropanoate group at the C6 position can be hydrolyzed to provide the 6-ethyl substituted N-heterocycles, which exhibit useful emission properties upon protonation.
收录类别:EI;SCOPUS;SCIE
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054876018&doi=10.1039%2fc8qo00887f&partnerID=40&md5=fc520389b8ff98acb00a50a822dbdf54
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