标题:Synthesis of Planar Chiral [2.2]Paracyclophanyl Imidazo[1,5-a]pyridinium Salts for the Rhodium-Catalyzed Asymmetric Arylation
作者:Wang, Dengxia; Ma, Yudao; He, Fuyan; Duan, Wenzeng; Zhao, Lei; Song, Chun
作者机构:[Wang, Dengxia; Ma, Yudao; He, Fuyan; Duan, Wenzeng; Zhao, Lei; Song, Chun] Shandong Univ, Dept Chem, Jinan 250100, Shandong, Peoples R China.
通讯作者:Ma, YD
通讯作者地址:[Ma, YD]Shandong Univ, Dept Chem, Shanda S Rd 27, Jinan 250100, Shandong, Peoples R China.
来源:SYNTHETIC COMMUNICATIONS
出版年:2013
卷:43
期:6
页码:810-825
DOI:10.1080/00397911.2011.610548
关键词:Aldehyde; asymmetric arylation; N-heterocyclic carbene; [2;; 2]paracyclophane; planar chirality
摘要:Several novel flexibility-restricted imidazo[1,5-a]pyridinium triflates (abbreviated as imidazolium salts) were synthesized from (4S p,13R p)-(-)-4-amino-13-bromo[2.2]paracyclophane and pyridylaldehyde. These imidazolium salts can be used as nitrogen-containing heterocyclic carbene precursors in asymmetric catalysis and here they are applied in the Rh-catalyzed asymmetric 1,2-addition of arylboronic acids to aldehydes. After optimizing the catalytic situations and testing a series of substrates, moderate enantioselectivity and good yield were obtained.
收录类别:SCOPUS;SCIE
WOS核心被引频次:8
Scopus被引频次:8
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84871847539&doi=10.1080%2f00397911.2011.610548&partnerID=40&md5=59458e72f1c08b26356f6f499e123270
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