标题：Neuropsychological development in school-aged children after surgery or transcatheter closure for ventricular septal defect
作者：Jin, Youpeng; Liu, Jinlong; Wang, Wei; Wang, Yujuan; Yin, Yi; Xin, Xiaowei; Han, Bo
作者机构：[Jin, Youpeng; Liu, Jinlong; Wang, Wei; Wang, Yujuan; Yin, Yi; Xin, Xiaowei; Han, Bo] Shandong Univ, Shandong Prov Hosp, Jinan 250021, Shandong, Peopl 更多
通讯作者地址：[Han, B]Shandong Univ, Shandong Prov Hosp, Jinan 250021, Shandong, Peoples R China.
关键词：Ventricular septal defect; Pediatrics; Neuropsychological development
摘要：ObjectivesWe aimed to assess neuropsychological development in school-aged children with ventricular septal defect (VSD) after surgery or transcatheter closure.MethodsWe included 31 children with VSD who underwent surgery and 35 who underwent transcatheter closure and their age- and sex-matched best friends as normal controls and parents. The Halstead-Reitan Battery was used to measure psychological and behavioral functions of children.ResultsThe mean finger-tapping time (left hand) was significantly lower for children with than without VSD (P<0.05). For non-handedness tactual performance, the mean time was significantly longer for surgery than interventional therapy groups and controls (P<0.05). The number of remembered locations was significantly lower for surgery than interventional therapy groups and controls (P<0.05). The correct number of music rhythms was significantly lower for the surgery than control group (P<0.05). Children with and without VSD did not differ in the correct number of first-group music rhythms. Nevertheless, for second- and third-group music rhythms, the correct number was significantly lower for the surgery than interventional therapy groups and controls (P<0.05). The correct number of third-group music rhythms was significantly lower for only the interventional therapy than control group.ConclusionSchool-aged children with VSD had normal IQ levels after surgery or interventional therapy but decreased fine-motor and auditory discrimination abilities as well as visual spatial disorder. Children with and without VSD did not differ in general tasks, but abilities on more complex and difficult tasks were lower for children with VSD. Impairments were greater after surgery than interventional therapy.