标题：Effect of a school-based educational intervention on HPV and HPV vaccine knowledge and willingness to be vaccinated among Chinese adolescents : a multi-center intervention follow-up study
作者：Zhang, Xi; Liu, Chun-rong; Wang, Zeng-zhen; Ren, Ze-fang; Feng, Xiang-xian; Ma, Wei; Gao, Xiao-hong; Zhang, Rong; Brown, Matthew D.; 更多 作者机构：[Zhang, Xi] Peking Univ, Key Lab Carcinogenesis & Translat Res, Beijing Off Canc Prevent & Control, Minist Educ Beijing,Canc Hosp & Inst, Beijing 1001 更多
通讯作者地址：Li, J (corresponding author), Sichuan Univ, West China Sch Publ Hlth, Dept Occupat & Environm Hlth, Chengdu 610041, Peoples R China.; Li, J (correspon 更多
关键词：HPV awareness; HPV vaccine; Educational intervention; Chinese; adolescents
摘要：Background: Middle school students are recommended as the primary target population for human papillomavirus (HPV) vaccination. This study aimed to assess HPV and HPV vaccine knowledge, and to evaluate the effect of a school-based educational intervention, immediately and one year later, on HPV knowledge and vaccine acceptability among adolescents in mainland China.; Methods: A school-based interventional follow-up study was conducted in seven representative cities in mainland China from May 2015 to May 2017. "Train-the-trainer" strategy was employed to educate school teachers in this study. Students aged 13 to 14 years old were assigned to intervention classes and control classes. All students were required to complete the baseline questionnaire. Students in the intervention classes were given a 45-minute lecture regarding HPV and HPV vaccine knowledge and were then asked to complete a post-education questionnaire. One year later, all students were asked to complete the post-education questionnaire again.; Results: Baseline HPV knowledge was low among Chinese adolescents, with only 12.6% and 15.7% of students having heard of HPV and HPV vaccines, respectively. After the intervention, the level of HPV-related knowledge increased immediately, and students with higher knowledge levels of HPV and HPV vaccines were more willing to get vaccinated. One year after the intervention, the knowledge of HPV and HPV vaccines was dramatically diminished. However, knowledge was significantly higher in intervention classes compared to control classes.; Conclusions: Knowledge and awareness of HPV and vaccination are generally deficient among Chinese adolescents. School-based health education was very effective in improving awareness and positive attitudes about HPV and HPV vaccines within a short time. Integrating health education on HPV into the existing school-based sexual health curriculum could be an effective way to increase HPV vaccination coverage and help to eliminate preventable HPV-associated cancers in China. (C) 2020 The Authors. Published by Elsevier Ltd.