标题:Phenolic alkaloids from the aerial parts of Dracocephalum heterophyllum
作者:Wang, Limei; Wang, Shuqi; Yang, Shuang; Guo, Xiaojiang; Lou, Hongxiang; Ren, Dongmei
作者机构:[Wang, Limei; Wang, Shuqi; Yang, Shuang; Guo, Xiaojiang; Lou, Hongxiang; Ren, Dongmei] Shandong Univ, Dept Nat Prod Chem, Key Lab Chem Biol, Minist Ed 更多
通讯作者:Ren, DM
通讯作者地址:[Ren, DM]Shandong Univ, Dept Nat Prod Chem, Key Lab Chem Biol, Minist Educ,Sch Pharmaceut Sci, 44 Wenhuaxi Rd, Jinan 250012, Peoples R China.
来源:PHYTOCHEMISTRY
出版年:2012
卷:82
页码:166-171
DOI:10.1016/j.phytochem.2012.06.021
关键词:Dracocephalum heterophyllum; Lamiaceae; Flavonoidal alkaloid; Imidazole; alkaloid; Chiral HPLC; Absolute configuration
摘要:Chemical examination of aerial parts of Dracocephalum heterophyllum resulted in isolation of phenolic alkaloids, including two flavonoidal alkaloids, drahebephins A and B, one imidazole alkaloid with a phenolic substituent, drahebenine, together with 15 other known compounds. Their structures were established by extensive spectroscopic data analyses. Due to the stereogenic center in the pyrrolidin-2-one ring, the flavonoidal alkaloids are chiral, although they were isolated as racemates. The enantiomers were separated by HPLC using a chiral phase and stereochemically characterized by circular dichroism (CD) spectroscopy. The structure of compound drahebenine was established by X-ray crystallography. (C) 2012 Elsevier Ltd. All rights reserved.
收录类别:SCOPUS;SCIE
WOS核心被引频次:7
Scopus被引频次:10
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84865200904&doi=10.1016%2fj.phytochem.2012.06.021&partnerID=40&md5=1d8c32d027b9e5f04386e6dc42e0b414
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