标题:Synthesis,Crystal Structure and URAT1 Inhibitory Activity of 2-((5-Bromo-4-((4-cyclobutylnaphth-1-yl)methyl)-4H-1,2,4-triazol-3-yl)thio)acetic Acid
作者:张宪生;辛晓;刘巍;谢亚非;刘长鹰;王建武;赵桂龙;
作者机构:[张宪生;辛晓;刘巍;谢亚非;刘长鹰;王建武;赵桂龙]School of Chemistry and Chemical Engineering,Shandong University;[张宪生;辛晓;刘巍;谢亚非;刘长鹰;王建武; 更多
来源:结构化学
出版年:2017
期:09
页码:1425-1432
关键词:synthesis;crystal structure;URAT1 inhibitor;lesinurad
摘要:The title compound 1 was prepared from 1-bromonaphthalene and cyclobutanone in 11 steps, and its structure was determined by single-crystal X-ray diffraction for its monohydrate. The title compound 1 crystallizes as its monohydrate(C_(19)H_(18)BrN_3O_2S·H_2O, M_r = 450.35) in triclinic, space group ...
资源类型:期刊论文
原文链接:http://kns.cnki.net/kns/detail/detail.aspx?FileName=JGHX201709003&DbName=CJFQ2017
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