标题：Hydroxyapatite Fibers: A Review of Synthesis Methods
作者：Qi, Mei-Li; He, Kun; Huang, Zhen-Nan; Shahbazian-Yassar, Reza; Xiao, Gui-Yong; Lu, Yu-Peng; Shokuhfar, Tolou
作者机构：[Qi, Mei-Li; He, Kun; Xiao, Gui-Yong; Lu, Yu-Peng] Shandong Univ, Minist Educ, Key Lab Liquid Solid Struct Evolut & Proc Mat, Jinan 250061, Shandong, 更多
通讯作者地址：[Qi, ML]Shandong Univ, Minist Educ, Key Lab Liquid Solid Struct Evolut & Proc Mat, Jinan 250061, Shandong, Peoples R China;[Qi, ML]Shandong Univ, Sch 更多
摘要：Hydroxyapatite (HA) exhibits excellent biocompatibility, bioactivity, osteoconductivity, non-toxicity and so on, making it a perfect candidate for biomedical applications. However, HA is not qualified to be used in load-bearing sites due to its poor flexural strength and fracture toughness. Design, synthesis and application of fibrous HA is a promising strategy to overcome the inherent brittleness. This review provides a brief description of HA and hydroxyapatite fiber (HAF), then introduces different synthesis methods of HAF and highlights the inherent merits and drawbacks involved in each method. Finally, the future perspectives in this active research area are given. The purpose of this review is to acquaint the reader with this promising new field of biomaterials research and with emphasis on recent techniques to obtain continuous, uniform and long HAF.