标题：Erythrocytosis caused by giant chromophobe renal cell carcinoma: a case report indicating a 9-year misdiagnosis of polycythemia vera
作者：Guo Renbo;Liang Yiran;Yan Lei;Xu Zhonghua;Ren Juchao
作者机构：[Guo Renbo] Department of Urology, Shandong Cancer Hospital Affiliated to Shandong University, Ji'nan, Shandong 250117, China.;[Liang Yiran] Departmen 更多
通讯作者地址：[Ren, JC]Shandong Univ, QiLu Hosp, Dept Urol, Jinan 250012, Shandong, Peoples R China.
关键词：Chromophobe renal cell carcinoma;Polycythemia vera;Erythrocytosis;Misdiagnosis
摘要：Background:Erythrocytosis,a rare paraneoplastic syndrome,generally occurs in patients with clear cell renal cell carcinoma and has never been reported in patients with chromophobe renal cell carcinoma.Case presentation:We report a case of a young man suffering from a giant (22-cm) mass on his left kidney.Because of a history of polycythemia vera,the patient had been treated for the condition for 9 years.Radical nephrectomy was successfully performed,and the postoperative pathologic examination confirmed a diagnosis ofchromophobe renal cell carcinoma.Unexpectedly,the symptom of erythrocytosis disappeared after the surgery.Further examination and analysis were performed,and we finally attributed his erythrocytosis to chromophobe renal cell carcinoma.Conclusions:Chromophobe renal cell carcinoma could cause erythrocytosis,but the clear-cut mechanism needs further research.Secondary erythrocytosis such as those related with renal tumors should be taken into consideration during the diagnosis of polycythemia vera.