标题：Nutrition education guided by Dietary Guidelines for Chinese Residents on metabolic syndrome characteristics, adipokines and inflammatory markers
作者：Zhang, Shi-xiu; Guo, Hong-wei; Wan, Wen-tao; Xue, Kun
作者机构：[Zhang, Shi-xiu; Guo, Hong-wei; Wan, Wen-tao; Xue, Kun] Fudan Univ, Dept Nutr & Food Hyg, Sch Publ Hlth, Shanghai 200032, Peoples R China.; [Zhang, 更多
通讯作者地址：[Guo, HW]Fudan Univ, Dept Nutr, Sch Publ Hlth, 130 Dongan Rd, Shanghai 200032, Peoples R China.
来源：ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION
关键词：the metabolic syndrome; nutrition education; adiponectin; leptin; tumor; necrosis factor-alpha
摘要：Objective: The objective of this study was to test whether "Dietary Guidelines for Chinese Residents" have beneficial effects on anthropometric and metabolic variables, adipokines and inflammatory markers in metabolic syndrome patients. Methods & Procedures: A multi-stage sampling method was applied to select metabolic syndrome patients in two districts of Shanghai. Two hundred and seventy-two metabolic syndrome patients were divided into control and intervention groups according to their district. Nutrition education guided by "Dietary Guidelines for Chinese Residents" was performed in the intervention group for one year. Results: Nutrition-related knowledge, attitudes and behavior were improved in the intervention group. Potassium intake and food to total energy ratio for grain, vegetable and fruit increased while sodium intake as well as fat to total energy ratio decreased in the intervention group compared to the control group (p<0.05). Correspondently, the intervention group significantly improved its waist circumference, waist to hip ratio, high-density lipoprotein cholesterol, adiponectin, leptin and tumor necrosis factor-a compared to the control group (p<0.05). Waist circumference changes from baseline to end of the study in the intervention and the control groups were -3.9 +/- 0.3 and -2.3 +/- 0.4 cm respectively. There was a significant difference between the two groups (p=0.004). Means of waist circumference, waist to hip ratio, leptin and tumor necrosis factor-a were lower, and high density lipoprotein-cholesterol was higher in the intervention group than the control group (p<0.05). Conclusion: This study confirmed "Dietary Guidelines for Chinese Residents" had beneficial effects on anthropometric, lipids, adipokines and inflammatory markers in metabolic syndrome patients.