标题:Predictive value of diffusion-weighted MR imaging in early response to chemoradiotherapy of esophageal cancer: a meta-analysis
作者:Cheng B.; Yu J.
作者机构:[Cheng, B] Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong University, Jinan, China;[ Yu, J] Department of Radiatio 更多
来源:Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
出版年:2019
卷:32
期:4
DOI:10.1093/dote/doy065
关键词:apparent diffusion coefficient; chemoradiotherapy; diffusion-weighted MR imaging; esophageal cancer; treatment response
摘要:The results of diffusion-weighted MR imaging (DW-MRI) in predicting early response to chemoradiotherapy in patients with esophageal cancer varied in different studies. We performed this meta-analysis to evaluate the predictive values of DW-MRI and compare the diagnostic efficacy of different apparent diffusion coefficients (ADCs). A comprehensive literature search was performed to identify relevant articles published before November 2017. The quality of study was assessed using Quality Assessment of Diagnostic Accuracy Studies-2. The pooled sensitivity, specificity, diagnostic odds ratio (DOR), and area under receiver operating characteristic curve of ADC values were calculated to determine the diagnostic performance. Seven studies with a total of 236 patients were included. The pooled sensitivity, specificity, DOR, and area under curve were 93% (95% CI 77%-98%), 85% (95% CI 72%-93%), 78 (95% CI 15-401), and 0.91 (95% CI 0.89-0.94), respectively, for the ▵ADC; and 75% (95% CI 62%-84%), 90% (95% CI 67%-97%), 26 (95% CI 6-110), and 0.85 (95% CI 0.82-0.88), respectively, for the post-ADC. For pre-ADC, meta-analysis was not performed because of conflicting results. In conclusions, our results demonstrate that DW-MRI has good performance for evaluating the response to chemoradiation therapy in patients with esophageal cancer. ▵ADC and post-ADC are promising reliable and valuable predictors. © The Author(s) 2018. Published by Oxford University Press on behalf of International Society for Diseases of the Esophagus.
收录类别:SCOPUS
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063955612&doi=10.1093%2fdote%2fdoy065&partnerID=40&md5=5941979072f893091f1ae906d1b073bc
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