标题:Effect of Obesity and Leptin Level on Migraineurs
作者:Zhang Ligong; Qin Jinjin; Chen Chunfu; Li Congcong; Diao Xiaojun
作者机构:[Zhang Ligong; Qin Jinjin; Chen Chunfu; Li Congcong; Diao Xiaojun] Shandong Univ, Shandong Prov Hosp, Dept Neurol, Jinan 250100, Shandong, Peoples R C 更多
通讯作者:Chen, CF
通讯作者地址:[Chen, CF]Shandong Univ, Shandong Prov Hosp, Dept Neurol, Jinan 250100, Shandong, Peoples R China.
来源:MEDICAL SCIENCE MONITOR
出版年:2015
卷:21
页码:3270-3274
关键词:Leptin; Migraine Disorders; Obesity, Abdominal
摘要:Background: The aim of this study was to analyze the effects of obesity and leptin levels on patients with migraine, and to observe the change of leptin levels in migraineurs.; Material/ Methods: We enrolled 52 migraine patients from the Headache Clinic in Shandong Provincial Hospital into a randomized controlled trial with another 52 age-, sex-, and BMI-matched healthy subjects as controls. Leptin levels in all subjects were determined by radioimmunoassay.; Results: Compared with the control group, the migraineurs revealed no significant change in leptin levels (P>0.05). Multivariate Logistic regression analysis showed that neither abdominal obesity nor leptin had significant impact on migraine clinical features. Total body obesity had a significant effect on the frequency (OR=4.248), duration (OR= 3.167), and intensity (OR= 5.225) of the headache.; Conclusions: Total body obesity affected headache frequency, intensity, and duration, while leptin levels did not.
收录类别:SCOPUS;SCIE
WOS核心被引频次:6
Scopus被引频次:6
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84945962338&doi=10.12659%2fMSM.894666&partnerID=40&md5=ff6c939cc122a9f1770f5f9c318c3e2b
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