标题：Systematic Review and Meta-Analysis of the Association between Ambient Nitrogen Dioxide and Respiratory Disease in China
作者：Sun, Jiyao; Barnes, Andrew J.; He, Dongyang; Wang, Meng; Wang, Jian
作者机构：[Sun, Jiyao; He, Dongyang; Wang, Meng; Wang, Jian] Shandong Univ, Sch Hlth Care Management, Key Lab Hlth Econ & Policy Res, Natl Hlth & Family Plannin 更多
通讯作者地址：[Wang, J]Shandong Univ, Sch Hlth Care Management, Key Lab Hlth Econ & Policy Res, Natl Hlth & Family Planning Commiss Peoples Repub, 44 West Wenhua Rd 更多
来源：INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
关键词：nitrogen dioxide; respiratory disease; hospital admission; China
摘要：Objective: This study aimed to assess the quantitative effects of short-term exposure of ambient nitrogen dioxide (NO2) on respiratory disease (RD) mortality and RD hospital admission in China through systematic review and meta-analysis. Methods: A total of 29 publications were finally selected from searches in PubMed, Web of Science, CNKI andWanfang databases. Generic inverse variance method was used to pool effect estimates. Pooled estimates were used to represent the increased risk of RD mortality and RD hospital admission per 10 mu g/m(3) increase in NO2 concentration. Results: Positive correlations were found between short-term NO2 exposure and RD in China. RD mortality and RD hospital admission respectively increased by 1.4% (95% CI: 1.1%, 1.7%) and 1.0% (95% CI: 0.5%, 1.5%) per 10 mu g/m(3) increase in NO2 concentration. Differences were observed across geographic regions of China. The risk of RD mortality due to NO2 was higher in the southern region (1.7%) than in the north (0.7%). Conclusions: Evidence was found that short-term exposure to NO2 was associated with an increased risk of RD mortality and RD hospital admission in China and these risks were more pronounced in the southern regions of the country, due in part to a larger proportion of elderly persons with increased susceptibility to NO2 in the population compared with the north.