标题：Phytic acid/graphene oxide nanocomposites modified electrode for electrochemical sensing of dopamine
作者：Wang, Donglei; Xu, Fei; Hu, Jiajie; Lin, Meng
作者机构：[Wang, Donglei; Xu, Fei; Hu, Jiajie; Lin, Meng] Shandong Univ, Sch Chem & Chem Engn, Key Lab Colloid & Interface Chem State, Educ Minist, Jinan 250100 更多
通讯作者地址：[Lin, M]Shandong Univ, Sch Chem & Chem Engn, Key Lab Colloid & Interface Chem State, Educ Minist, Jinan 250100, Peoples R China.
来源：MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
关键词：Dopamine; Phytic acid; Nanocomposites; Graphene oxide; Electrochemical; sensor
摘要：An electrochemical sensor for determining dopamine was developed by modifying phytic acid/graphene oxide (PA/GO) nanocomposites onto a glassy carbon electrode (GCE). PA functionalized GO was prepared by an ultra-sonication method. Subsequently, the PA/GO nanocomposites were drop-casted on a glassy carbon substrate. The structural feature of the PA/GO modified GCE was confirmed by attenuated total reflection infrared (ATR-IR) spectroscopy. The proposed electrochemical sensor was applied to detect various concentrations of DA by differential pulse voltammetry (DPV). The PA/GO/GCE was considered to be highly sensitive to DA in the range of 0.05-10 mu M. In addition, the PA/GO/GCE demonstrated high electrochemical selectivity toward DA in the presence of ascorbic acid (AA) and uric acid (UA). The prepared electrochemical DA sensor was applied for detection of DA in dopamine hydrochloride injection and spiked samples of human urine with satisfactory results. (C) 2016 Elsevier B.V. All rights reserved.