标题:利用肺炎克雷伯氏菌以葡萄糖和磷酸铵盐为底物生产2,3-丁二醇
作者:秦加阳;肖梓军;马翠卿;谢能中;刘培海;许平
作者机构:[Qin, J] State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, China;[ Xiao, Z] State Key Laboratory of Microbial Technolog 更多
通讯作者:Qin, J.
通讯作者地址:[Xu, P]Shandong Univ, State Key Lab Microbial Technol, Jinan 250100, Peoples R China.
来源:中国化学工程学报(英文版)
出版年:2006
卷:14
期:1
页码:132-136
DOI:10.1016/S1004-9541(06)60050-5
关键词:2,3-butanediol production,optimization,fed-batch,Klebsiella pneumoniae
摘要:The production of 2,3-butanediol by Klebsiella pneumoniae from glucose supplemented with different salts was studied. A suitable medium composition was defined by response surface experiments. In a medium containing glucose and (NH4)2HPO4, the strain could convert 137.0g of glucose into 52.4g of 2,3-butanediol and 8.4g of acetoin in shaking flasks. The diol yield amounted to 90% of its theoretical value and the productivity was 1-1.5g·L-1·h-1. In fed-batch fermentation, the yield and productivity of diol were further enhanced by maintaining the pH at 6.0. Up to 92.4g of 2,3-butanediol and 13.1g of acetoin per liter were obtained from 215.0g of glucose per liter. The diol yield reached 98% of its theoretical value and the productivity was up to 2.1g·L-1·h-1.
收录类别:EI;CSCD;SCOPUS;SCIE
WOS核心被引频次:72
Scopus被引频次:83
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-33646156601&doi=10.1016%2fS1004-9541%2806%2960050-5&partnerID=40&md5=173d56339fe52a56afab0d729b291e69
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