标题：Large moderately-differentiated ovarian Sertoli-Leydig cell tumor in a 13-year-old female: A case report
作者：Zhang, Hui; Hao, Jing; Li, Chun-Yan; Li, Tao; Mu, Yu-Lan
作者机构：[Zhang, Hui; Li, Chun-Yan; Li, Tao; Mu, Yu-Lan] Shandong Univ, Shandong Prov Hosp, Dept Obstet & Gynecol, 324 jingwu Weiqi Rd, Jinan 250012, Shandong, 更多
通讯作者地址：[Mu, YL]Shandong Univ, Shandong Prov Hosp, Dept Obstet & Gynecol, 324 jingwu Weiqi Rd, Jinan 250012, Shandong, Peoples R China.
关键词：ovary; Sertoli-Leydig cell tumor; hyperthyroidism; masculinization
摘要：Sertoli-Leydig cell tumor of the ovary, also known as androblastoma, is a rare neoplasm from the group of sex cord-stromal tumors of the ovary. The tumor accounts for < 0.5% of all primary ovarian neoplasms. The clinical signs and symptoms of Sertoli-Leydig cell tumors can be associated with either hormonal production or the presence of a mass-occupying lesion. In the current study, a 13-year-old female was diagnosed with a stage I-c ovarian Sertoli-Leydig cell tumor following abdominal pain and distension. One month after a right oophorectomy, the follow-up magnetic resonance imaging scan was negative for residual or recurrent tumor. The overall 5-year survival rate for moderately-differentiated (grade 2) and poorly-differentiated (grade 3) Sertoli-Leydig cell tumors is 80%, and long-term follow-up is therefore highly advised in this patient.