标题:Association between interleukin-18 promoter variants and tacrolimus pharmacokinetics in Chinese renal transplant patients
作者:Xing, Jiazhen;Zhang, Xiaoqing;Fan, Junwei;Shen, Bin;Men, Tongyi;Wang, Jianning
作者机构:[Xing, J] Department of Urology Surgery, Shandong Qianfoshan Hospital, Taishan Medical College, Shandong, China;[ Zhang, X] Department of Pharmacy, Sh 更多
通讯作者:Men, TY
通讯作者地址:[Men, TY]16766 Jingshi Rd, Jinan, Peoples R China.
来源:European journal of clinical pharmacology
出版年:2015
卷:71
期:2
页码:191-198
DOI:10.1007/s00228-014-1785-8
关键词:CYP3A5;IL-18;SNPs;Tacrolimus pharmacokinetics;Renal transplantation
摘要:Interleukin 18 (IL-18) is a potent proinflammatory cytokine thought to down-regulate cytochrome P450 (CYP) enzyme activities. This study aimed to assess the potential influence of two functional single nucleotide polymorphisms (SNPs) in the IL-18 promoter region on the tacrolimus pharmacokinetics in Chinese renal transplant patients.
收录类别:SCOPUS;SCIE
WOS核心被引频次:3
Scopus被引频次:3
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84925519595&doi=10.1007%2fs00228-014-1785-8&partnerID=40&md5=450ef234688a6ffea6fa56d0b0e4a2f6
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