标题: Precision medicine in myasthenia graves: begin from the data precision.
作者: Li, Hai-Feng; Hong, Yu; Xie, Yanchen; Hao, Hong-Jun; Sun, Ren-Cheng
作者机构:[ Li, Hai-Feng; Li HF] 1 Department of Neurology, Qilu Hospital of Shandong University, Jinan 250012, China ; 2 Department of Clinical Medicine, Unive 更多
来源: Annals of translational medicine
出版年:2016
卷: 4
期: 6
DOI:10.21037/atm.2016.02.16
摘要: Myasthenia gravis (MG) is a prototypic autoimmune disease with overt clinical and immunological heterogeneity. The data of MG is far from individually precise now, partially due to the rarity and heterogeneity of this disease. In this review, we provide the basic insights of MG data precision, including onset age, presenting symptoms, generalization, thymus status, pathogenic autoantibodies, muscle involvement, severity and response to treatment based on references and our previous studies. Subgroups and quantitative traits of MG are discussed in the sense of data precision. The role of disease registries and scientific bases of precise analysis are also discussed to ensure better collection and analysis of MG data.
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资源类型:期刊论文
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