标题:Transition-metal-free synthesis of indole-fused dibenzo[b,f][1,4]oxazepines via Smiles rearrangement
作者:Hu, Fangdong; Liu, Huanhuan; Jia, Jiong; Ma, Chen
作者机构:[Hu, Fangdong; Liu, Huanhuan; Jia, Jiong; Ma, Chen] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China.; [Ma, Chen] Chinese Acad Med 更多
通讯作者:Ma, Chen
通讯作者地址:[Ma, C]Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China;[Ma, C]Chinese Acad Med Sci, Inst Mat Med, State Key Lab Bioact Subst & Func 更多
来源:ORGANIC & BIOMOLECULAR CHEMISTRY
出版年:2016
卷:14
期:47
页码:11076-11079
DOI:10.1039/c6ob02098d
摘要:A one-pot transition-metal-free approach for the synthesis of indole-fused dibenzo[b,f][1,4]oxazepines from 2-(1H-indol-2-yl)phenol and 1,2-dihalobenzenes or 2 halonitroarenes has been developed. The proposed mechanism for this transformation features a Smiles rearrangement favoured over a direct intramolecular nucleophilic cyclization, which affords the corresponding products in different regioselectivities. This reaction also features simple reaction conditions and wide functional group tolerance.
收录类别:EI;SCOPUS;SCIE
WOS核心被引频次:8
Scopus被引频次:8
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84999672261&doi=10.1039%2fc6ob02098d&partnerID=40&md5=39fe0a2d4acf92e336fffdec3d360340
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