标题:The value of 18F-FDG PET/CT in patient with neurofibromatosis type 1
作者:Ren J.; Yang G.; Zhou J.; Fu Z.
作者机构:[Ren, J] Department of Radiology, Jining No. 1 People's Hospital, Jining Shandong, China;[ Yang, G] Department of Nuclear Medicine, China, Shandong Ac 更多
通讯作者:Fu, Z(1364878759@qq.com)
通讯作者地址:[Fu, Z] Department of Imaging, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical SciencesChina;
来源:Medicine (United States)
出版年:2018
卷:97
期:20
DOI:10.1097/MD.0000000000010648
关键词:18 F-FDG PET/CT; café-au-lait macules; neurofibromatosis
摘要:Rationale: Neurofibromatosis type one (NF1) is characterized by cutaneous and nervous lesions, and the tendency to form plexiform neurofibromas (PNFs). PNFs may undergo malignant transformation into a malignant peripheral nerve sheath tumors (MPNSTs). MPNSTs often carry an significant morbidity and mortality. Patient concerns: A 17-year-old man with gradually increased multiple subcutaneous soft lesions. He also presented with numerous lentigines and multiple café-au-lait macules on his body. Diagnoses: These were collagen neurofibroma, which were definitively diagnosed by pathology. NF1 was eventually diagnosed. Interventions: These lesions were abnormal uptake of radiotracer, when he underwent positron emission tomography (PET) with fluorine-18-fluorodeoxyglucose (FDG) scanning. Standard uptake value (SUV) and other parameters can help to distinguish benign and malignant lesions in patient with NF1. He was underwent serials 18 F-FDG PET/CT examinations to followed up, in order to monitor these lesions malignant transformation. Outcomes: So far, these subcutaneous soft lesions were not malignant transformation. Lessons: 18 F-FDG PET/CT is being increasingly used as an imaging modality to discover the systemic lesions and to discriminate between benign and malignant plexiform neurofibromas. © 2018 the Author(s).
收录类别:SCOPUS
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047328559&doi=10.1097%2fMD.0000000000010648&partnerID=40&md5=e67e565f5046e78cb35001af1d2b0c1e
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