标题：Advances in the study of luminescence probes for proteins
作者：Changxia Sun;Jinghe Yang;Lei Li;Xia Wu;Yang Liu;Shufang Liu
作者机构：[Sun, C] Key Lab. Colloid Interface Chem. E., Department of Chemistry, Shandong University, Jinan 250100, China;[ Yang, J] Key Lab. Colloid Interface 更多
通讯作者地址：[Sun, CX]Shandong Univ, Dept Chem, Key Lab Colloid & Interface Chem Educ Minist, Jinan 250100, Peoples R China.
来源：Journal of chromatography, B. Analytical technologies in the biomedical and life sciences
摘要：Spectral probes (or labels) have been widely used for the investigation and determination of proteins and have made considerable progress. Traditional luminescence probes include fluorescent derivatizing reagents, fluorescent probes and chemiluminescence probes which continue to develop. Of them, near infrared (NIR) fluorescent probes are especially suitable for the determination of biomolecules including proteins, so their development has been rapid. Novel luminescence probes (such as nanoparticle probes and molecular beacons) and resonance light scattering probes recently appeared in the literature. Preliminary results indicate that they possess great potential for ultrasensitive protein detection. This review summarizes recent developments of the above-mentioned probes for proteins and 195 references are cited.