标题：Selective versus non-selective removal for dental caries: a systematic review and meta-analysis
作者：Li, Ti; Zhai, Xiangkai; Song, Feifei; Zhu, Hongguang
作者机构：[Li, Ti; Zhai, Xiangkai; Song, Feifei; Zhu, Hongguang] Peoples Hosp Weifang, Dept Dent, 151 Guangwen St, Weifang 261041, Shandong, Peoples R China.
通讯作者：Zhu, HG;Zhu, HG
通讯作者地址：[Zhu, HG]Peoples Hosp Weifang, Dept Dent, 151 Guangwen St, Weifang 261041, Shandong, Peoples R China;[Zhu, HG]Shandong Univ, Sch Stomatol, Shandong Pr 更多
来源：ACTA ODONTOLOGICA SCANDINAVICA
关键词：Meta-analysis; dental caries; selective caries removal; non-selective; caries removal
摘要：Objective: Selective and non-selective methods for caries removal were controversial so far, thus we aimed to compare the efficacy of selective and non-selective caries removal by conducting meta-analysis of randomized controlled trials (RCTs).; Materials and methods: Eligible RCTs studies comparing selective caries removal with non-selective caries removal were retrieved by searching PubMed, EMBASE and Cochrane Library till 15 July 2017. The pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated for outcome indictors, including pulpal exposure, pulpal symptoms and failure using Inverse variance-random effects or Mantel-Haenszel-fixed effects models.; Results: Totally, seven studies were eligible for the meta-analysis. Compared with the non-selective caries removal group, the risk of pulpal exposure was significantly reduced in the selective caries removal group (OR=0.11, 95% CI: 0.04-0.30). No significant difference was observed in pulpal symptoms (OR=0.79, 95% CI: 0.30-2.12) and failure (OR=1.40, 95% CI: 0.69-2.84) between the groups.; Conclusions: The efficacy of selective caries removal appears comparable to that of non-selective caries removal in children, with similar pulpal symptoms and failure, but selective caries removal may result in a low incidence of pulpal exposure. However, larger-scale RCTs with long-term follow-up are required to confirm this conclusion.