标题:Research and development of novel histone deacetylase inhibitors
作者:Hao Fang;
作者机构:[Hao Fang]Institute of Medicinal Chemistry,School of Pharmaceutical Sciences,Shandong University
来源:Proceedings of the 4th CPA-RSC Symposium on Medicinal Chemistry: Epigenetics as Targets for Drug Discovery
出版年:2013
关键词:Research and development of novel histone deacetylase inhibitors;
摘要:Histone deacetylases(HDACs),a family of enzymes involved in epigenetic modification,have been validated as promising targets for antitumor drug design.Recently we developed series of novel HDACs inhibitors(HDACIs), among which tetrahydroisoquinoline-based derivatives,1-3 N-hydroxycinnamamide-base...
资源类型:会议论文
原文链接:http://kns.cnki.net/kns/detail/detail.aspx?FileName=YYWS201311003015&DbName=IPFD2014
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