标题:Dearomative [4+2] Cycloaddition of Oxindole-Embedded ortho-Quinone Methides with 2,5-Dialkylfurans
作者:Shen, Yao-Bin; Li, Shuai-Shuai; Liu, Xicheng; Yu, Liping; Liu, Qing; Xiao, Jian
作者机构:[Shen, Yao-Bin; Li, Shuai-Shuai; Xiao, Jian] Qingdao Agr Univ, Coll Chem & Pharmaceut Sci, Qingdao 266109, Shandong, Peoples R China.; [Yu, Liping] 更多
通讯作者:Xiao, J;Yu, LP
通讯作者地址:[Xiao, J]Qingdao Agr Univ, Coll Chem & Pharmaceut Sci, Qingdao 266109, Shandong, Peoples R China;[Yu, LP]Qingdao Agr Univ, Coll Landscape Architecture 更多
来源:ADVANCED SYNTHESIS & CATALYSIS
出版年:2019
卷:361
期:6
页码:1453-1458
DOI:10.1002/adsc.201801509
关键词:2,5-dialkylfuran; spirooxindole; oxindole-embedded o-QMs;; dearomatization; [4+2] cycloaddition
摘要:2,5-Dialkylfurans were facilely converted to pharmaceutically significant spiro[chroman-4,3'-oxindole] scaffolds via an organocatalytic dearomative [4 + 2] cycloaddition with oxindole-embedded ortho-quinone methides. This method featured mild reaction conditions, simple operation, good yields, and excellent diastereoselectivities.
收录类别:SCIE
资源类型:期刊论文
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