标题:Cascade One-Pot Method To Synthesize Isoquinolin-1(2H)-ones with alpha-Bromo Ketones and Benzamides via Pd-catalyzed C-H Activation
作者:Xie, Caixia; Dai, Zhen; Niu, Yadi; Ma, Chen
作者机构:[Xie, Caixia; Dai, Zhen; Niu, Yadi; Ma, Chen] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Shandong, Peoples R China.; [Ma, Chen] Chinese Acad 更多
通讯作者:Ma, Chen
通讯作者地址:[Ma, C]Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Shandong, Peoples R China;[Ma, C]Chinese Acad Med Sci, Inst Mat Med, State Key Lab Bioact Su 更多
来源:JOURNAL OF ORGANIC CHEMISTRY
出版年:2018
卷:83
期:4
页码:2317-2323
DOI:10.1021/acs.joc.7b03224
摘要:A cross-coupling strategy of palladium-catalyzed ortho-C-H bond activation and intramolecular addition of N-C annulation to synthesize isoquinolin-1(2H)-ones has been developed. A wide range of alpha-bromo ketones with different substituents proceeded smoothly in this reaction, and varieties of isoquinolin-1(2H)-one derivatives were obtained in moderate to good yields.
收录类别:EI;SCIE
资源类型:期刊论文
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