标题:Influence of vinyltrimethoxysilane on properties of methylene blue-loaded Silica@Octacalcium phosphate as drug delivery
作者:Li, Yadong ;Bai, Zhijie ;Wang, Baiwei ;Sun, Yanbiao ;Yang, Zhanzhong ;Li, Chengfeng
作者机构:[Li, Yadong ;Bai, Zhijie ;Wang, Baiwei ;Sun, Yanbiao ;Yang, Zhanzhong ;Li, Chengfeng ] School of Materials Science and Engineering, Shandong Universit 更多
通讯作者:Li, Chengfeng
来源:Kuei Suan Jen Hsueh Pao/Journal of the Chinese Ceramic Society
出版年:2016
卷:44
期:8
页码:1213-1219
DOI:10.14062/j.issn.0454-5648.2016.08.19
摘要:Methylene blue-loaded silica (silica-MB) particles were prepared by a modified Stöber process with MB and vinyltrimethoxysilane (A171). Silica-MB@OCP powders were obtained after the deposition of octacalcium phosphate (OCP) on the surface of silica-MB by a modified Pechini process. The addition of A171 during the sol-gel process affects the phases, constitutes and core-shell structure of samples. The addition amount of A171, core-shell structure and pH value of culture solution have effects on the release behaviors of MB, i.e., cumulative release and ratio of released MB monomers versus dimers. Unlike silica-MB, the degradation percents of silica-MB@OCP increase significantly in phosphate buffer saline and lysosome-like buffer.
© 2016, Editorial Department of Journal of the Chinese Ceramic Society. All right reserved.
收录类别:EI
资源类型:期刊论文
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