标题：Improvement of L-Arabinose Fermentation by Modifying the Metabolic Pathway and Transport in Smccharomyces cerevisiae
作者：Chengqiang Wang;Yu Shen;Yanyan Zhang;Fan Suo;Jin Hou;Xiaoming Bao
作者机构：The State Key Laboratory of Microbial Technology, Shandong University, Shan Da Nan Road No. 27
来源：BioMed research international
摘要：The L-arabinose utilization pathway was established in Saccharomyces cerevisiae, by expressing the codon-optimized araA, araB, and araD genes of Lactobadllus plantarum. After overexpressing the TALI, TKL1, RPE1, RKI1, and GAL2 genes and adaptive evolution, the L-arabinose utilization of the recombinant strain became efficient. The resulting strain displayed a maximum specific growth rate of 0.075 h~(-1), a maximum specific L-arabinose consumption rate of 0.61 g h~(-1) g~(-1) dry cell weight, and a promising ethanol yield of 0.43 gg~(-1) from L-arabinose fermentation.