标题:Synthesis of new planar chiral [2.2]paracyclophane Schiff base ligands and their application in the asymmetric Henry reaction
作者:Xin, DY;Ma, YD;He, FY
作者机构:[Xin, D] Department of Chemistry, Shandong University, Shanda South Road No. 27, Jinan, 250100, China;[ Ma, Y] Department of Chemistry, Shandong Unive 更多
通讯作者:Ma, YD
通讯作者地址:[Ma, YD]Shandong Univ, Dept Chem, Shanda S Rd 27, Jinan 250100, Peoples R China.
来源:Tetrahedron, Asymmetry: The International Journal for Repid Publication on all Aspects of Asymmetry in Orgainc, Inorganic, Organometallic, Physical and Bio-Organic Chemistry
出版年:2010
卷:21
期:3
页码:333-338
DOI:10.1016/j.tetasy.2010.02.007
关键词:CATALYTIC ENANTIOSELECTIVE CYCLOPROPANATION;COMPLEXES;ALDEHYDES;PARACYCLOPHANE;2ND-GENERATION;HYDROGENATION;DERIVATIVES;N;O-LIGANDS;EFFICIENT;ESTERS
摘要:A series of new planar and central chiral ligands based on [2.2]paracyclophane backbones were designed and prepared from enantiomerically pure 4-amino-13-bromo[2.2]paracyclophane and commercially available chiral amino alcohols. Their application in a copper-catalyzed asymmetric Henry reaction resulted in secondary alcohols with high yield and excellent selectivity for active aldehydes (up to 94% ee). This is a successful example of employing planar chiral [2.2]paracyclophane ligands in copper-catalyzed reaction.
收录类别:SCOPUS;SCIE
WOS核心被引频次:49
Scopus被引频次:52
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-77949295470&doi=10.1016%2fj.tetasy.2010.02.007&partnerID=40&md5=b59cce8d22306e8fcdd950fef1e6bf2d
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