标题:Monoclonal antibody-related drugs for cancer therapy
作者:Li G.; Wang S.; Xue X.; Qu X.; Liu H.
作者机构:[Li, G] Shandong Luye Pharmaceutical Group Co., Ltd., Yantai, Shandong, China;[ Wang, S] Department of Emergency, Yantaishan Hostital, Yantai, Shandon 更多
通讯作者地址:Liu, H.电子邮件: huiping_ra@hotmail.com
来源:Drug Discoveries and Therapeutics
出版年:2013
卷:7
期:5
页码:178-184
DOI:10.5582/ddt.2013.v7.5.178
摘要:Much progress has been made during the last few decades in the treatment of malignancies. Many types of cancer cells comprising the tumor mass carry molecular markers that are not expressed or are expressed at much lower levels in normal cells. These findings provide new leads to drug design and development of therapeutic strategies involving monoclonal antibodies (mAbs) or related antibody drugs to treat malignancies. This article reviews recent advances in this targeting approach with a focus on the evolution and current use of prospective antibody drugs as effective ways to treat cancer. Additionally, the development of prospective antibody-drug conjugates will also be briefly described.
收录类别:SCOPUS
Scopus被引频次:14
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84900544606&doi=10.5582%2fddt.2013.v7.5.178&partnerID=40&md5=e09f3b4ac370987509efa5e8968ffd8f
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