标题:Establishment of a human induced pluripotent stem cell line (SDQLCHi005-A) from a patient with mastocytosis carrying heterozygous mutation in KIT gene
作者:Zhang, Haiyan; Ma, Yanyan; Yan, Beibei; Yang, Xiaomeng; Li, Yue; Guan, Jingyun; Dong, Rui; Liu, Yi; Gai, Zhongtao
作者机构:[Zhang, Haiyan; Ma, Yanyan; Yang, Xiaomeng; Li, Yue; Guan, Jingyun; Dong, Rui; Liu, Yi; Gai, Zhongtao] Shandong Univ, Pediat Res Inst, Qilu Childrens 更多
通讯作者:Liu, Y
通讯作者地址:[Liu, Y]Shandong Univ, Pediat Res Inst, Qilu Childrens Hosp, Jinan 250022, Shandong, Peoples R China.
来源:STEM CELL RESEARCH
出版年:2019
卷:40
DOI:10.1016/j.scr.2019.101565
摘要:We established an induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells of a Chinese neonate with mastocytosis carrying heterozygous mutation (c.2447A > T (p.D816V)) in KIT gene by episomal vector (EV) reprogramming system. This iPSC line carrying KIT gene mutation, was free of exogenous gene, showed a normal karyotype, expressed pluripotency markers and exhibited differentiation potential.
收录类别:SCOPUS;SCIE
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85072042983&doi=10.1016%2fj.scr.2019.101565&partnerID=40&md5=b2d8823d4cade98447859482b7589759
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