标题：Riboflavin/ultravoilet light-mediated crosslinking for fungal keratitis
作者机构：[Li, Z] Department of Ophthalmology, Provincial Hospital Affiliated to Shandong University, No. 324, Jing 5 Road, Ji'nan City, 250021;[ Shandong Provi 更多
通讯作者地址：[Mu, GY]Shandong Univ, Prov Hosp, Dept Ophthalmol, 324,Jing 5 Rd, Jinan 250021, Shandong, Peoples R China.
来源：British journal of ophthalmology
摘要：Collagen crosslinking (CXL) has been used to treat cases with bacterial, Acanthamoeba and fungal keratitis with encouraging results. In this study, we present the clinical outcomes in cases with fungal keratitis that received riboflavin/ ultravoilet light A (UVA) light-mediated crosslinking.Patients with microbiologically proven fungal keratitis were included in this study. A written consent was obtained from all the patients. The study protocol was approved by the ethics committee of the Provincial Hospital. Initial treatment was commenced in the form of hourly 5% natamycin eye drops and 0.3% tobramycin eye drops four times a day. A decision was taken to perform CXL after no response to treatment or an exacerbation of infection was observed. Under topical anaesthesia, the epithelium surrounding the infiltrate was removed.