标题:Molecular mechanism of substrate specificity for heparan sulfate2-O-sulfotransferase
作者:刘纯慧;Juzheng Sheng;Juno M.Krahn;Lalith Perera;Yongmei Xu;Po-Hung Hsieh;Wenfang Dou;Jian Liu;Lars C.Pedersen;
作者机构:[刘纯慧;Juzheng Sheng;Juno M.Krahn;Lalith Perera;Yongmei Xu;Po-Hung Hsieh;Wenfang Dou;Jian Liu;Lars C.Pedersen]Institute of Biochemical and Biotechnol 更多
会议名称:2014年中国药学大会暨中国药师周
来源:2014年中国药学大会暨第十四届中国药师周论文集
出版年:2014
关键词:Heparan sulfate 2-O-sulfatransferase;substrate specificity;crystal structure;site-directed mutagenesis;oligosaccharide
摘要:Heparan sulfate(HS)is an abundant polysaccharide in the animal kingdom with essential physiological functions.HS is composed of sulfated saccharides that are biosynthesized through a complex pathway involving multiple enzymes.In vivo regulation of this process remains unclear.HS 2-Osulfotransferase(...
资源类型:会议论文
原文链接:http://kns.cnki.net/kns/detail/detail.aspx?FileName=YYWS201410003196&DbName=CPFD2015
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