标题:Co-assemblies of polyoxometalate {Mo72Fe30}/double-tailed magnetic-surfactant for magnetic-driven anchorage and enrichment of protein
作者:Zhao, Wenrong; Cui, Jiwei; Hao, Jingcheng; Van Horn, J. David
作者机构:[Zhao, Wenrong; Cui, Jiwei; Hao, Jingcheng] Shandong Univ, Minist Educ, Key Lab Colloid & Interface Chem, Jinan 250100, Shandong, Peoples R China.; 更多
通讯作者:Cui, JW;Hao, JC;Cui, JW;Hao, JC
通讯作者地址:[Cui, JW; Hao, JC]Shandong Univ, Minist Educ, Key Lab Colloid & Interface Chem, Jinan 250100, Shandong, Peoples R China;[Cui, JW; Hao, JC]Shandong Uni 更多
来源:JOURNAL OF COLLOID AND INTERFACE SCIENCE
出版年:2019
卷:536
页码:88-97
DOI:10.1016/j.jcis.2018.10.037
关键词:Co-assembly; Polyoxometalate; Double-tailed mag-surfactant; Magnetic; transporting vehicles; Protein molecule
摘要:Covalent grafting and electrostatic-driven assembly have been two strategies in constructing well-defined polyoxometalate (POM) assemblies to produce specific morphologies and desirable properties. The modification of anionic counter-ions of amphiphilic compounds in POM-surfactant hybrid systems is still unexploited. Herein, we report the co-assembly of a synthetic double-tailed magnetic surfactant (MagSurf), (C-18)(2)C2N+[FeCl4](-), and POM, {Mo72Fe30}. The magnetic aggregate (POM/MagSurf) results from the building up hierarchical structures at a time-dependent interface. In this construct, both the MagSurfs and {Mo72Fe30} POMs contribute to and mutually strengthen the magnetization of the designed magnetic assembles. Interestingly, the POM/MagSurf aggregates are compatible with aqueous mixtures and successfully employed to serve as magnetic transporting vehicles to anchor and deliver a protein molecule, myoglobin (Mb). Upon applying a magnetic field (0.3 T), the magnetic aggregates induced a directional migration and enrichment of the Mb protein (71-90%). During this process, the protein/POM/MagSurf complexes exhibited strong interactions facilitating stable anchoring and efficient enrichment of the Mb. (C) 2018 Elsevier Inc. All rights reserved.
收录类别:SCOPUS;SCIE
Scopus被引频次:1
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055170874&doi=10.1016%2fj.jcis.2018.10.037&partnerID=40&md5=ef3281f39288ca76689e8fcb24b4ccc4
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