标题:Concurrent involved-field radiotherapy and XELOX in gastric cancer patients with postoperative oligometastatic recurrence
作者:Xu, Cuiping; Xie, Jian; Liang, Ning; Wang, Junrong; Qiao, Lili; Luo, Hui; Zhang, Jing Xin; Zhang, Jiandong
作者机构:[Xu, Cuiping; Xie, Jian; Liang, Ning; Qiao, Lili; Zhang, Jiandong] Shandong Univ, Qianfoshan Hosp, Dept Radiat Oncol, Jinan 250014, Shandong, Peoples 更多
通讯作者:Zhang, JD
通讯作者地址:[Zhang, JD]Shandong Univ, Qianfoshan Hosp, Dept Radiat Oncol, 16766 Jingshi Rd, Jinan 250014, Shandong, Peoples R China.
来源:JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
出版年:2014
卷:10
期:8
页码:C267-C271
DOI:10.4103/0973-1482.151487
关键词:Gastric cancer; oligometastatic recurrence; radiochemotherapy; XELOX
摘要:Purpose: The aim of this study was to retrospectively observe gastric adenocarcinoma patients with postoperative oligometastatic recurrence and investigated the effects of concurrent involved-field radiotherapy (RT) and XELOX on progression-free survival (PFS).; Patients and Methods: From 2008 to 2011, 246 patients underwent curative resection of gastric carcinoma was enrolled. A retrospective review was performed on 34 patients with distant recurrence. Among them, 19 patients were oligometastases patients, where 13 patients received involved-field RT with a dose of 40-60 Gy by an intensity-modulated RT technique and concurrent XELOX chemotherapy, four patients were treated with XELOX chemotherapy alone (oxaliplatin 130 mg/m(2), capecitabine 1000 mg/m(2), twice daily, 3 week each cycle), and two patients with only brain metastasis were not included in the analysis.; Results: The median PFS was 11 months in the 13 oligometastatic patients who received concurrent involved-field RT and XELOX. The oligometastatic patients receiving concurrent radiochemotherapy trended toward a better median PFS when compared with those receiving chemotherapy alone.; Conclusions: For patients with postoperative oligometastatic recurrence, concurrent involved-field RT and XELOX showed better responses and was a choice for first-line treatment.
收录类别:SCOPUS;SCIE
WOS核心被引频次:1
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84924085612&doi=10.4103%2f0973-1482.151487&partnerID=40&md5=d9a976ed088f2d5f55c78b59f1186b10
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