标题：Electrochemical co-reduction synthesis of graphene/nano-gold composites and its application to electrochemical glucose biosensor
作者：Wang, Xiaolin; Zhang, Xiaoli
作者机构：[Wang, Xiaolin; Zhang, Xiaoli] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China.
会议名称：12th International Fischer Symposium
会议日期：JUN 03-07, 2012
关键词：Biosensor; Graphene/nano-Au composite; Electrochemical co-reduction; synthesis; Glucose oxidase; Glucose detection
摘要：A simple, green and controllable approach was employed for electrochemical synthesize of the graphene/nano-Au composites. The process was that graphene oxide and HAuCl4 was electrochemically co-reduced onto the glassy carbon electrode (GCE) by cyclic voltammetry in one step. The obtained graphene/nano-Au/GCE exhibited high electrocatalytic activity toward H2O2, which resulted in a remarkable decrease in the overpotential of H2O2 electrochemical oxidation compared with bare GCE. Such electrocatalytic behavior of the graphene/nano-Au/GCE permitted effective low-potential amperometric biosensing of glucose via the incorporation of glucose oxidase (GOD) with graphene/nano-Au. An obvious advantage of this enzyme electrode (graphene/nano-Au/GOD/GCE) was that the graphene/nano-Au nanocomposites provided a favorable microenvironment for GOD and facilitated the electron transfer between the active center of GOD and electrode. The immobilized GOD showed a direct, reversible redox reaction. Furthermore, the graphene/nano-Au/GOD/GCE was used as a glucose biosensor, displaying a low detection limit of 17 mu M (S/N = 3), a high sensitivity of 56.93 mu AmM-1 cm(-2), acceptable reproducibility, very good stability, selectivity and anti-interference ability. (C) 2013 Elsevier Ltd. All rights reserved.