标题：Amanita fuliginea poisoning with thrombocytopenia: A case series
作者：Wang, Qiang; Sun, Meifeng; Lv, Hailin; Lu, Peng; Ma, Chengjun; Liu, Yun; Liu, Shuqin; Tong, Haiqing; Hu, Zhao; Gao, Yanxia
作者机构：[Wang, Qiang; Lv, Hailin; Lu, Peng; Ma, Chengjun; Liu, Yun; Tong, Haiqing; Gao, Yanxia] Shandong Univ Qingdao, Dept Nephrol, Qilu Hosp, 758 Hefei Rd, 更多
通讯作者地址：[Gao, YX]Shandong Univ Qingdao, Dept Nephrol, Qilu Hosp, 758 Hefei Rd, Qingdao, Peoples R China.
关键词：Amanita fuliginea; Thrombocytopenia; Acute liver failure
摘要：Amanita fuliginea (A. fuliginea) poisoning is an uncommon and potentially fatal amatoxin exposure. We present 3 cases of severe A. fuliginea poisoning associated with thrombocytopenia in China. Three patients consumed foraged A. fuliginea and developed nausea, vomiting, abdominal pain, and diarrhea. They were transferred from primary clinics to our hospital 19-39 h after mushroom ingestion. They all presented with acute hepatic injury, coagulopathy, thrombocytopenia (6-41 x 10(9)/L), and positive fecal occult blood. Intravenous fluids and antioxidants were administered immediately after admission. Fibrinogen and platelets were given to patients A, B and C. Patient A developed fulminant liver failure and died on day 5 after mushroom exposure. Patients B and C recovered and were discharged on days 11 and 9, respectively. The main targets of A. fuliginea poisoning are the liver and digestive tract. To our knowledge this is the first report of thrombocytopenia associated with A. fuliginea ingestion.