标题：Composition, isolation, purification and biological activities of Sargassum fusiforme polysaccharides: A review
作者：Zhang, Rui; Zhang, Xinxin; Tang, Yingxue; Mao, Jinlong
作者机构：[Zhang, Rui; Zhang, Xinxin; Mao, Jinlong] Shandong Univ Tradit Chinese Med, Sch Pharm, Jinan 250355, Shandong, Peoples R China.; [Zhang, Rui] Shando 更多
通讯作者：Mao, Jinlong;Mao, JL
通讯作者地址：[Mao, JL]Shandong Univ Tradit Chinese Med, Sch Pharm, Jinan 250355, Shandong, Peoples R China.
关键词：Sargassum fusiforme polysaccharides; Alginic acid; Fucoidan; Laminaran;; Biological activity
摘要：Sargassum fusiforme polysaccharides, acidic water-soluble polysaccharides extract from Sargassum fusiforme, are mainly composed of alginic acid, fucoidan and laminaran. Alginic acid is carboxyl-containing polysaccharide formed by joining beta-D-mannuronic acid and alpha-L-guluronic acid through beta-(1 -> 4)/alpha-(1 -> 4) glycosidic bond. Fucoidan, a natural water-soluble sulfated heteropolysaccharide with fucose and sulfuric acid groups as the core structure, is mainly linked by L-fucose through alpha-(1 -> 3) glycosidic bond and has the strongest biological activity. Laminaran is mainly composed of beta-D-glucose through beta-(1 -> 3) glycosidic bond linkage. Sargassum fusiforme polysaccharides have a variety of pharmacological activities, including antioxidant, anti-tumor, promoting immunity, anti-aging, prompting bone growth, lowering blood glucose, anti-coagulation, anti-virus, anti-bacteria, anti-fatigue, promoting growth and development, and skin protection. These activities are closely related to the functions of fucoidan in Sargassum fusiforme polysaccharides, which fucoidan is able to strengthen immune system and antioxidation in human body. In this review, the composition, the isolation and purification, and the biological activities of Sargassum fusiforme polysaccharides are discussed and can bereference for further study.