标题：Diversity and multiple functions of lectins in shrimp immunity
作者：Wang, Xian-Wei; Wang, Jin-Xing
作者机构：[Wang, Xian-Wei; Wang, Jin-Xing] Shandong Univ, Sch Life Sci, Key Lab Plant Cell Engn & Germplasm Innovat, Minist Educ,Shandong Prov Key Lab Anim Cell 更多
通讯作者地址：[Wang, JX]Shandong Univ, Sch Life Sci, Key Lab Plant Cell Engn & Germplasm Innovat, Minist Educ,Shandong Prov Key Lab Anim Cells & De, Jinan 250100, S 更多
来源：DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
关键词：Shrimp; Crustacean; Lectin; Innate immunity; Pattern recognition
摘要：Lectins play important roles in many biological processes, including protein trafficking, cell signaling, pathogen recognition, as effector molecules, and so on, because of their capacity to bind carbohydrates. Presently, seven groups of lectins have been identified in shrimp: C-type, L-type, P-type, M-type, fibrinogen-like domain lectins, galectins, and calnexin/calreticulin. These lectins have different structures, diverse expression patterns, and multiple functions in the shrimp immune response. This review summarizes the research progress and analyzes the diversity of shrimp lectins, focusing mainly on the C-type lectin family. Shrimp C-type lectins show considerable diversity in their domain architectures, sugar substrates, tissue distributions, expression patterns responding to pathogen challenge and functions in shrimp immunity. (C) 2012 Elsevier Ltd. All rights reserved.