标题：Ixeris sonchifolia: a review of its traditional uses, chemical constituents, pharmacology and modern applications
作者：Li K.-W.; Liang Y.-Y.; Xie S.-M.; Niu F.-J.; Guo L.-Y.; Liu Z.-H.; Zhou C.-Z.; Wang L.-Z.
作者机构：[Li, K.-W] College of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China;[ Liang, Y.-Y] College of Pharmacy, Shandon 更多
通讯作者地址：[Zhou, C.-Z] College of Pharmacy, Shandong University of Traditional Chinese Medicine, Daxue Road 4655, China;
来源：Biomedicine and Pharmacotherapy
关键词：Chemical constituents; Clinical studies; Ixeris sonchifolia(IS); Pharmacological activities; Quality control; Traditional uses
摘要：Ixeris sonchifolia (IS), principally its dried form, is widely used as traditional and folk medicines in some Asian countries, especially China. In this review, we summarized its traditional uses, chemical constituents, quality control measures, pharmacological activities, therapeutic evaluation, toxicity evaluation and clinical applications. 130 chemical constituents isolated from IS have been reported, including flavones, sesquiterpenes, triterpenes, phenylpropanoids, organic acids and others. They showed various pharmacological activities, such as protecting cardiocerebral vascular system, anticancer effect and antiviral etc. The quality control evaluation studies, clinical applications, other possible applications and suggestions for future research also were discussed. The aim of this review is to critically appraise the available literature and suggest directions for further development of IS to improve its medical value and use. © 2020 The Authors