标题:Distribution, industrial applications, and enzymatic synthesis of D-amino acids
作者:Gao, Xiuzhen; Ma, Qinyuan; Zhu, Hailiang
作者机构:[Gao, Xiuzhen; Zhu, Hailiang] Shandong Univ Technol, Sch Life Sci, Zibo 255049, Peoples R China.; [Ma, Qinyuan] Weifang Ensign Ind Co Ltd, Ctr Techn 更多
通讯作者:Gao, Xiuzhen
通讯作者地址:[Gao, XZ]Shandong Univ Technol, Sch Life Sci, Zibo 255049, Peoples R China.
来源:APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
出版年:2015
卷:99
期:8
页码:3341-3349
DOI:10.1007/s00253-015-6507-3
关键词:D-Amino acids; Enzymatic synthesis; Asymmetric amination; D-Amino acid; dehydrogenase
摘要:d-Amino acids exist widely in microbes, plants, animals, and food and can be applied in pharmaceutical, food, and cosmetics. Because of their widespread applications in industry, d-amino acids have recently received more and more attention. Enzymes including d-hydantoinase, N-acyl-d-amino acid amidohydrolase, d-amino acid amidase, d-aminopeptidase, d-peptidase, l-amino acid oxidase, d-amino acid aminotransferase, and d-amino acid dehydrogenase can be used for d-amino acids synthesis by kinetic resolution or asymmetric amination. In this review, the distribution, industrial applications, and enzymatic synthesis methods are summarized. And, among all the current enzymatic methods, d-amino acid dehydrogenase method not only produces d-amino acid by a one-step reaction but also takes environment and atom economics into consideration; therefore, it is deserved to be paid more attention.
收录类别:EI;SCIE
WOS核心被引频次:22
资源类型:期刊论文
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