标题：Engineering of filamentous fungi for efficient conversion of lignocellulose: Tools, recent advances and prospects
作者：Liu G.; Qu Y.
作者机构：[Liu, G] State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, China, Shandong Key Laboratory of Water Pollution Control 更多
通讯作者地址：[Qu, Y] State Key Laboratory of Microbial Technology, Shandong UniversityChina;
关键词：Cellulase; Consolidated bioprocessing; Fungi; Genetic engineering; Lignocellulose
摘要：Filamentous fungi, as the main producers of lignocellulolytic enzymes in industry, need to be engineered to improve the economy of large-scale lignocellulose conversion. Investigation of the cellular processes involved in lignocellulolytic enzyme production, as well as optimization of enzyme mixtures for higher hydrolysis efficiency, have provided effective targets for the engineering of lignocellulolytic fungi. Recently, the development of efficient genetic manipulation systems in several lignocellulolytic fungi opens up the possibility of systems engineering of these strains. Here, we review the recent progresses made in the engineering of lignocellulolytic fungi and highlight the research gaps in this area. © 2018