标题:Scaparvin A, A novel caged cis-clerodane with an unprecedented C-6/C-11 bond, and related diterpenoids from the liverwort scapania parva
作者:Guo, D.-X.;Zhu, R.-X.;Wang, X.-N.;Wang, L.-N.;Wang, S.-Q.;Lin, Z.-M.;Lou, H.-X.
作者机构:[Guo, D.-X] Department of Natural Products Chemistry, School of Pharmaceutical Sciences, Shandong University, No. 44 West Wenhua Road, Jinan 250012, C 更多
通讯作者:Lou, HX
通讯作者地址:[Lou, HX]Shandong Univ, Sch Pharmaceut Sci, Dept Nat Prod Chem, 44 W Wenhua Rd, Jinan 250012, Peoples R China.
来源:Organic letters
出版年:2010
卷:12
期:19
页码:4404-4407
DOI:10.1021/ol1019458
摘要:Figure Presented. A novel caged cis-clerodane diterpenoid, scaparvin A, possessing an unprecedented C-6/C-11 bond and a ketal ring, as well as four new cis-clerodane derivatives, scaparvins B-E, were isolated from the Chinese liverwort Scapania parva. Their absolute structures were elucidated by analysis of NMR and CD data coupled with electronic circular dichroism (ECD) calculations. It was proposed that an enzymatic intramolecular aldol reaction was the key step in the biogenetic pathway of scaparvin A.
收录类别:SCOPUS;SCIE
WOS核心被引频次:25
Scopus被引频次:29
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-77957139106&doi=10.1021%2fol1019458&partnerID=40&md5=745a2d20c16bbc3b7414d35b63ceb9b2
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