标题:Synthesis, Structure Characterization, and X-ray Crystallography of Novel 1 -Benzyl-3-phenyl-1H-pyrazole-5-carboxylate Derivatives with a Carbohydrate Moiety
作者:Song Lian;Jin Ting Liu;Liang Wen Zheng;Wei Yong Liu;Bao Xiang Zhao
作者机构:[Lian, S] Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China;[ Liu, J.-T] Institut 更多
通讯作者:Liu, JT
通讯作者地址:[Liu, JT]Shandong Univ, Sch Chem & Chem Engn, Inst Organ Chem, Jinan 250100, Peoples R China.
来源:Journal of Carbohydrate Chemistry
出版年:2011
卷:30
期:1
页码:1-15
DOI:10.1080/07328303.2011.583371
关键词:Synthesis;Structure;Pyrazole;Xylose;X-ray
摘要:A series of novel (2S,3R,4S,5R)-3,4,5-triacetoxy-tetrahydro-2i/-pyran-2-yl l-benzyl-3-phenyl-lH-pyrazole-5-carboxylate derivatives (3) were synthesized by the reaction of 2,3,4-tri-O-acetyl-a-D-xylopyranosyl bromide (2) and l-benzyl-3-phenyl-lH-pyrazole-5-carboxylic acid (1) in the presence of sodium bicarbonate and tetrabutylammonium bromide in dichloromethane at reflux temperature. The structures of new compounds were determined by IR and ~1H NMR spectroscopy and HR mass spectrometry (HRMS), and the configuration of the newly generated chiral carbon (C-l) in the xylose ring was tentatively assigned based on the X-ray crystallographic structure of 3d and 3g.
收录类别:SCOPUS;SCIE
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-79960182149&doi=10.1080%2f07328303.2011.583371&partnerID=40&md5=1593379f1217fda9fcf04513e9f61cff
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