标题:qnrVC-like gene located in a novel complex class 1 integron harboring the ISCR1 element in an Aeromonas punctata strain from an aquatic environment in Shandong Province, China.
作者:Xia R;Guo X;Zhang Y;Xu H
作者机构:[Xia, R] State Key Laboratory of Microbial Technology, School of Life Science, Shandong University, 27 Shanda Nanlu, Jinan 250100, China;[ Guo, X] Sta 更多
通讯作者:Xu, H
通讯作者地址:[Xu, H]Shandong Univ, Sch Life Sci, State Key Lab Microbial Technol, 27 Shanda Nanlu, Jinan 250100, Shandong, Peoples R China.
来源:Antimicrobial Agents and Chemotherapy
出版年:2010
卷:54
期:8
页码:3471-3474
DOI:10.1128/AAC.01668-09
摘要:A qnrVC-like gene, qnrVC4, was found in a novel complex class 1 integron gene cassette array following the ISCR1 element and bla(PER-1) in a multidrug-resistant strain of the aquatic bacterium Aeromonas punctata. The deduced QnrVC4 protein sequence shares 45% to 81% amino acid identity with quinolone resistance determinants QnrB6, QnrA1, QnrS1, QnrC, QnrVC1, and QnrVC3. A Ser-83 to Ile amino acid substitution in gyrase A may be mainly responsible for ciprofloxacin resistance in this strain.
收录类别:SCOPUS;SCIE
WOS核心被引频次:44
Scopus被引频次:47
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-77955403183&doi=10.1128%2fAAC.01668-09&partnerID=40&md5=ffc222cc3d0d188ef2a2aed3549f492b
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