标题:Rearranged abietane diterpenoid hydroquinones from aerial parts of Ajuga decumbens Thunb
作者:Wang, Bo;Wang, Xiao-Ning;Shen, Tao;Wang, Shu-Qi;Guo, Dong-Xiao;Lou, Hong-Xiang
作者机构:[Wang, B] Department of Natural Products Chemistry, School of Pharmaceutical Sciences, Shandong University, No. 44 West Wenhua Road, Jinan 250012, Chi 更多
通讯作者:Lou, HX
通讯作者地址:[Lou, HX]Shandong Univ, Sch Pharmaceut Sci, Dept Nat Prod Chem, 44 W Wenhua Rd, Jinan 250012, Peoples R China.
来源:Phytochemistry Letters
出版年:2012
卷:5
期:2
页码:271-275
DOI:10.1016/j.phytol.2012.01.010
关键词:Ajuga decumbens;Abietane diterpenoids;Ajudecumins A;Cytotoxic
摘要:Four new rearranged abietane diterpenoid hydroquinones, ajudecumins A-D (1-4), together with two known rearranged abietane diterpenoids, three neo-clerodane diterpenoids, four megastigmane derivatives, two flavonoids as well as a bisabolene sesquiterpenoid were isolated from the aerial parts of Ajuga decumbens. Their structures were established on the basis of extensive spectroscopic analysis and the stereochemistry of 1 was confirmed by single-crystal X-ray diffraction analysis. Among the diterpenoids, compounds 1 and 3 exhibited moderate inhibitory activity on the proliferation of human breast cancer MCF-7 cells. (C) 2012 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.
收录类别:SCOPUS;SCIE
WOS核心被引频次:8
Scopus被引频次:9
资源类型:期刊论文
原文链接:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862804618&doi=10.1016%2fj.phytol.2012.01.010&partnerID=40&md5=88c452c53287d3d56ddd50ac17f7ce84
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