标题： Voxel Placement Precision for GABA-Edited Magnetic Resonance Spectroscopy.
作者： Bai, Xue; Harris, Ashley D; Gong, Tao; Puts, Nicolaas A J; Wang, Guangbin; Schar, Michael; Barker, Peter B; Edden, Richard A E
作者机构：[ Bai, Xue; Bai X] Department of Radiology, Qilu Hospital of Shandong University, Jinan, China.;[ Harris, Ashley D; Harris AD] Russell H. Morgan Depar 更多
来源： Open journal of radiology
摘要： The purpose of the present study was to assess the reproducibility of voxel placement for GABA-edited MRS. GABA-edited MRS data were acquired in 13 healthy volunteers from (3 cm)(3) voxel; and within the same session a second acquisition was independently prescribed. A three-dimensional voxel mask image was reconstructed in T1-image-space using the SVMask tool (in house software). Reproducibility of voxel placement was assessed using the Dice overlap coefficient, both within-subject and between-subject following co-registration of T1 images and transformation of voxel mask images to standard space. Within-subject overlap coefficients were 86% +/- 5%. Between-subject overlap coefficients were 75% +/- 10%. For the two voxel locations considered (occipital and sensorimotor), voxel overlap was very similar. Between-subject values are higher due to between-session effects, anatomical variability and volume mismatch in standard space. While surprisingly low in terms of volume overlap, the overlap coefficients correspond to acceptable linear displacements.