作者机构：[Pei, Ke; Wu, Jibiao] Shandong Univ Tradit Chinese Med, Coll Tradit Chinese Med, Jinan 250355, Peoples R China.; [Gui, Ting; Li, Chao; Gai, Zhibo] S 更多[Pei, Ke; Wu, Jibiao] Shandong Univ Tradit Chinese Med, Coll Tradit Chinese Med, Jinan 250355, Peoples R China.; [Gui, Ting; Li, Chao; Gai, Zhibo] Shandong Univ Tradit Chinese Med, Key Lab Tradit Chinese Med Class Theory, Minist Educ, Jinan 250355, Peoples R China.; [Zhang, Qian; Li, Yunlun] Shandong Univ Tradit Chinese Med, First Clin Med Coll, Jinan 250355, Peoples R China.; [Feng, Huichao] Shandong Univ Tradit Chinese Med, Acupuncture & Massage Coll, Jinan 250355, Peoples R China.; [Li, Yunlun] Shandong Univ Tradit Chinese Med, Affiliated Hosp, Jinan 250011, Peoples R China.; [Gai, Zhibo] Univ Zurich, Univ Zurich Hosp, Dept Clin Pharmacol & Toxicol, CH-8006 Zurich, Switzerland. 收起
通讯作者：Li, Y(yunlun.lee@hotmail.com)
通讯作者地址：Wu, JB (corresponding author), Shandong Univ Tradit Chinese Med, Coll Tradit Chinese Med, Jinan 250355, Peoples R China.; Gai, ZB (corresponding autho 更多Wu, JB (corresponding author), Shandong Univ Tradit Chinese Med, Coll Tradit Chinese Med, Jinan 250355, Peoples R China.; Gai, ZB (corresponding author), Shandong Univ Tradit Chinese Med, Key Lab Tradit Chinese Med Class Theory, Minist Educ, Jinan 250355, Peoples R China.; Li, YL (corresponding author), Shandong Univ Tradit Chinese Med, First Clin Med Coll, Jinan 250355, Peoples R China.; Li, YL (corresponding author), Shandong Univ Tradit Chinese Med, Affiliated Hosp, Jinan 250011, Peoples R China.; Gai, ZB (corresponding author), Univ Zurich, Univ Zurich Hosp, Dept Clin Pharmacol & Toxicol, CH-8006 Zurich, Switzerland. 收起
来源：BIOMED RESEARCH INTERNATIONAL
出版年：2020
卷：2020
DOI：10.1155/2020/3680397
摘要：The incidence of chronic kidney disease (CKD) is associated with major abnormalities in circulating lipoproteins and renal lipid metabolism. This article elaborates on the mechanisms of CKD and lipid uptake abnormalities. The viewpoint we supported is that lipid abnormalities directly cause CKD, resulting in forming a vicious cycle. On the theoretical and experiment fronts, this inference has been verified by elaborately elucidating the role of lipid intake and accumulation as well as their influences on CKD. Taken together, these findings suggest that further understanding of lipid metabolism in CKD may lead to novel therapeutic approaches.
