标题：Photodynamic therapy of intraductal papillary mucinous neoplasm
作者：Topazian, M.; Zhong, N.; Baron, T. H.; Vege, S. S.; Wang, K. K.
作者机构：[Topazian, M.; Baron, T. H.; Vege, S. S.; Wang, K. K.] Mayo Clin, Dept Internal Med, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA.; [Zhong, 更多
通讯作者地址：[Topazian, M]Mayo Clin, Dept Internal Med, Div Gastroenterol & Hepatol, 200 1st St SW, Rochester, MN 55905 USA.
摘要：Intraductal papillary mucinous neoplasm (IPMN) of the main pancreatic duct is usually treated by surgical excision of the affected pancreas. Non-operative ablative therapies have not been described. We treated IPMN of the pancreatic duct with photodynamic therapy (PDT) in a patient who was a poor operative candidate. Porfimer sodium was administered intravenously, and laser light was delivered by a diffusing catheter placed in the pancreatic duct during endoscopic retrograde cholangiopancreatography (ERCP). Imaging and biopsy findings of IPMN resolved after PDT, and symptoms also resolved. Metastatic cancer was diagnosed 2 years after PDT had been initiated. Pancreatic PDT was well tolerated in this case, and may be a therapeutic option for selected patients with IPMN of the main pancreatic duct.