标题：N,N '-Di-carboxymethyl perylene diimide functionalized magnetic nanocomposites with enhanced peroxidase-like activity for colorimetric sensing of H2O2 and glucose
作者：Chen, Miaomiao; Sun, Lifang; Ding, Yanan; Shi, Zhiqiang; Liu, Qingyun
作者机构：[Chen, Miaomiao; Sun, Lifang; Ding, Yanan; Liu, Qingyun] Shandong Univ Sci & Technol, Sch Chem & Environm Engn, Qingdao 266510, Peoples R China.; [S 更多
通讯作者：Liu, QY;Shi, ZQ
通讯作者地址：[Liu, QY]Shandong Univ Sci & Technol, Sch Chem & Environm Engn, Qingdao 266510, Peoples R China;[Shi, ZQ]Shandong Normal Univ, Sch Chem Chem Engn & Ma 更多
来源：NEW JOURNAL OF CHEMISTRY
摘要：In the present study, for the first time, N,N'-di-carboxymethyl perylene diimides (PDI) have been employed to functionalize Fe3O4 nanoparticles via a facile route. The as-prepared PDI-Fe3O4 nanocomposites have been developed as a novel enzyme mimetic and have demonstrated superior peroxidase-like activity to catalyze the oxidation of the peroxidase substrate 3,3',5,5'-tetramethylbenzidine (TMB) in the presence of H2O2 than that of pure Fe3O4 nanoparticles as well as other reported Fe-based peroxidase mimics. In addition, kinetic analysis has revealed that the catalytic reaction was in agreement with the typical Michaelis-Menten kinetics, and the PDI-Fe3O4 nanocomposites displayed a higher affinity towards substrates such as H2O2 and TMB. Moreover, fluorescence data have indicated that the catalytic behavior can be assessed by the electron transfer ability between H2O2 and TMB. Based on the advantages of PDI-Fe3O4 nanocomposites, such as better dispersity, easy separation, enhanced catalytic activity, sensitivity and selectivity for colorimetric detection of glucose, a colorimetric sensor was designed and used for the rapid detection of H2O2 and glucose in a short time.