标题：The anticancer effect of Huaier
作者：Song, Xiaojin;Li, Yaming;Zhang, Hanwen;Yang, Qifeng
作者机构：[Song, X] Department of Breast Surgery, Qilu Hospital, Shandong University, 44 Wenhua Xi Road, Jinan, Shandong 250012, China;[ Li, Y] Department of B 更多
通讯作者地址：[Yang, QF]Shandong Univ, Sch Med, Qilu Hosp, Dept Breast Surg, 44 Wenhua Xi Rd, Jinan 250012, Shandong, Peoples R China.
关键词：Huaier;cancer;apoptosis;angiogenesis;metastasis;immunomodulatory;cancer stem cell
摘要：Trametes robiniophila Murr. (Huaier) is a sandy beige mushroom found on the trunks of trees and has been widely used in traditional Chinese medicine (TCM) for 1,600 years. The anticancer effects of Huaier have attracted increasing worldwide interest in recent years. Accumulating evidence suggests that the anticancer mechanism of Huaier may be associated with various biological activities, such as inhibition of cell proliferation, anti-metastasis, interference with tumor angiogenesis and tumor-specific immunomodulatory effect. Animal and experimental studies suggest that Huaier is a promising anticancer agent. Further clinical research is warranted to illustrate the untapped chemopreventive and therapeutic potential of Huaier either alone or in conjunction with existing therapies.